Streptococcus pneumoniae in the heart subvert the host response through biofilm-mediated resident macrophage killing

For over 130 years, invasive pneumococcal disease has been associated with the presence of extracellular planktonic pneumococci, i.e. diplococci or short chains in affected tissues. Herein, we show that Streptococcus pneumoniae that invade the myocardium instead replicate within cellular vesicles an...

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Vydáno v:PLoS Pathog
Hlavní autoři: Shenoy, Anukul T., Brissac, Terry, Gilley, Ryan P., Kumar, Nikhil, Wang, Yong, Gonzalez-Juarbe, Norberto, Hinkle, Whitney S., Daugherty, Sean C., Shetty, Amol C., Ott, Sandra, Tallon, Luke J., Deshane, Jessy, Tettelin, Hervé, Orihuela, Carlos J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2017
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5589263/
https://ncbi.nlm.nih.gov/pubmed/28841717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006582
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