Streptococcus pneumoniae in the heart subvert the host response through biofilm-mediated resident macrophage killing

For over 130 years, invasive pneumococcal disease has been associated with the presence of extracellular planktonic pneumococci, i.e. diplococci or short chains in affected tissues. Herein, we show that Streptococcus pneumoniae that invade the myocardium instead replicate within cellular vesicles an...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Shenoy, Anukul T., Brissac, Terry, Gilley, Ryan P., Kumar, Nikhil, Wang, Yong, Gonzalez-Juarbe, Norberto, Hinkle, Whitney S., Daugherty, Sean C., Shetty, Amol C., Ott, Sandra, Tallon, Luke J., Deshane, Jessy, Tettelin, Hervé, Orihuela, Carlos J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5589263/
https://ncbi.nlm.nih.gov/pubmed/28841717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006582
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