Cell Invasion and Pyruvate Oxidase-Derived H(2)O(2) Are Critical for Streptococcus pneumoniae-Mediated Cardiomyocyte Killing

Streptococcus pneumoniae (the pneumococcus) is the leading cause of community-acquired pneumonia and is now recognized to be a direct contributor to adverse acute cardiac events. During invasive pneumococcal disease, S. pneumoniae can gain access to the myocardium, kill cardiomyocytes, and form bact...

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Bibliographic Details
Published in:Infect Immun
Main Authors: Brissac, Terry, Shenoy, Anukul T., Patterson, LaDonna A., Orihuela, Carlos J.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2017
Subjects:
Molecular Pathogenesis
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5736805/
https://ncbi.nlm.nih.gov/pubmed/29061707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00569-17
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