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Immunization of cervidized transgenic mice with multimeric deer prion protein induces self-antibodies that antagonize chronic wasting disease infectivity in vitro

Chronic wasting disease (CWD) is the most contagious prion disease. It is expanding rapidly in North America, was found recently in Europe, and the potential for transmission to humans cannot be excluded yet. We hypothesized that it is possible to prevent peripheral CWD infection and CWD prion shedd...

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שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Sci Rep
Main Authors: Abdelaziz, Dalia H., Thapa, Simrika, Abdulrahman, Basant, Lu, Li, Jain, Shikha, Schatzl, Hermann M.
פורמט: Artigo
שפה:Inglês
יצא לאור: Nature Publishing Group UK 2017
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC5585258/
https://ncbi.nlm.nih.gov/pubmed/28874781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-11235-8
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