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Immunization of cervidized transgenic mice with multimeric deer prion protein induces self-antibodies that antagonize chronic wasting disease infectivity in vitro

Chronic wasting disease (CWD) is the most contagious prion disease. It is expanding rapidly in North America, was found recently in Europe, and the potential for transmission to humans cannot be excluded yet. We hypothesized that it is possible to prevent peripheral CWD infection and CWD prion shedd...

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Podrobná bibliografie
Vydáno v:Sci Rep
Hlavní autoři: Abdelaziz, Dalia H., Thapa, Simrika, Abdulrahman, Basant, Lu, Li, Jain, Shikha, Schatzl, Hermann M.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5585258/
https://ncbi.nlm.nih.gov/pubmed/28874781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-11235-8
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