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Synthesis of sulfamoylbenzamide derivatives as HBV capsid assembly effector

The synthesis of novel series of sulfamoylbenzamides as HBV capsid assembly effector is reported. The structure was divided into five parts which were independently modified as part of our lead optimization. All synthesized compounds were evaluated for their anti-HBV activity and toxicity in human h...

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Bibliografiska uppgifter
I publikationen:Eur J Med Chem
Huvudupphovsmän: Sari, Ozkan, Boucle, Sebastien, Cox, Bryan D., Ozturk, Tugba, Russell, Olivia Ollinger, Bassit, Leda, Amblard, Franck, Schinazi, Raymond F.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2017
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5581232/
https://ncbi.nlm.nih.gov/pubmed/28688280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejmech.2017.06.062
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