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Synthesis of sulfamoylbenzamide derivatives as HBV capsid assembly effector

The synthesis of novel series of sulfamoylbenzamides as HBV capsid assembly effector is reported. The structure was divided into five parts which were independently modified as part of our lead optimization. All synthesized compounds were evaluated for their anti-HBV activity and toxicity in human h...

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Bibliografiske detaljer
Udgivet i:Eur J Med Chem
Main Authors: Sari, Ozkan, Boucle, Sebastien, Cox, Bryan D., Ozturk, Tugba, Russell, Olivia Ollinger, Bassit, Leda, Amblard, Franck, Schinazi, Raymond F.
Format: Artigo
Sprog:Inglês
Udgivet: 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5581232/
https://ncbi.nlm.nih.gov/pubmed/28688280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejmech.2017.06.062
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