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Synthesis of sulfamoylbenzamide derivatives as HBV capsid assembly effector

The synthesis of novel series of sulfamoylbenzamides as HBV capsid assembly effector is reported. The structure was divided into five parts which were independently modified as part of our lead optimization. All synthesized compounds were evaluated for their anti-HBV activity and toxicity in human h...

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書目詳細資料
發表在:Eur J Med Chem
Main Authors: Sari, Ozkan, Boucle, Sebastien, Cox, Bryan D., Ozturk, Tugba, Russell, Olivia Ollinger, Bassit, Leda, Amblard, Franck, Schinazi, Raymond F.
格式: Artigo
語言:Inglês
出版: 2017
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5581232/
https://ncbi.nlm.nih.gov/pubmed/28688280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejmech.2017.06.062
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