A carregar...
Autoinhibition of ETV6 DNA Binding Is Established by the Stability of Its Inhibitory Helix
The ETS transcriptional repressor ETV6 (or TEL) is autoinhibited by an α-helix that sterically blocks its DNA-binding ETS domain. The inhibitory helix is marginally stable and unfolds when ETV6 binds to either specific or non-specific DNA. Using NMR spectroscopy, we show that folding of the inhibito...
Na minha lista:
| Publicado no: | J Mol Biol |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5575937/ https://ncbi.nlm.nih.gov/pubmed/26920109 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2016.02.020 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|