Leveraging molecular datasets for biomarker-based clinical trial design in glioblastoma

BACKGROUND. Biomarkers can improve clinical trial efficiency, but designing and interpreting biomarker-driven trials require knowledge of relationships among biomarkers, clinical covariates, and endpoints. We investigated these relationships across genomic subgroups of glioblastoma (GBM) within our...

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Dettagli Bibliografici
Pubblicato in:Neuro Oncol
Autori principali: Tanguturi, Shyam K., Trippa, Lorenzo, Ramkissoon, Shakti H., Pelton, Kristine, Knoff, David, Sandak, David, Lindeman, Neal I., Ligon, Azra H., Beroukhim, Rameen, Parmigiani, Giovanni, Wen, Patrick Y., Ligon, Keith L., Alexander, Brian M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2017
Soggetti:
Basic and Translational Investigations
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5570228/
https://ncbi.nlm.nih.gov/pubmed/28339723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/now312
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