Leveraging molecular datasets for biomarker-based clinical trial design in glioblastoma

BACKGROUND. Biomarkers can improve clinical trial efficiency, but designing and interpreting biomarker-driven trials require knowledge of relationships among biomarkers, clinical covariates, and endpoints. We investigated these relationships across genomic subgroups of glioblastoma (GBM) within our...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Neuro Oncol
Main Authors: Tanguturi, Shyam K., Trippa, Lorenzo, Ramkissoon, Shakti H., Pelton, Kristine, Knoff, David, Sandak, David, Lindeman, Neal I., Ligon, Azra H., Beroukhim, Rameen, Parmigiani, Giovanni, Wen, Patrick Y., Ligon, Keith L., Alexander, Brian M.
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2017
Teme:
Basic and Translational Investigations
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5570228/
https://ncbi.nlm.nih.gov/pubmed/28339723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/now312
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