Clinical implementation of integrated whole-genome copy number and mutation profiling for glioblastoma

BACKGROUND: Multidimensional genotyping of formalin-fixed paraffin-embedded (FFPE) samples has the potential to improve diagnostics and clinical trials for brain tumors, but prospective use in the clinical setting is not yet routine. We report our experience with implementing a multiplexed copy numb...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Ramkissoon, Shakti H., Bi, Wenya Linda, Schumacher, Steven E., Ramkissoon, Lori A., Haidar, Sam, Knoff, David, Dubuc, Adrian, Brown, Loreal, Burns, Margot, Cryan, Jane B., Abedalthagafi, Malak, Kang, Yun Jee, Schultz, Nikolaus, Reardon, David A., Lee, Eudocia Q., Rinne, Mikael L., Norden, Andrew D., Nayak, Lakshmi, Ruland, Sandra, Doherty, Lisa M., LaFrankie, Debra C., Horvath, Margaret, Aizer, Ayal A., Russo, Andrea, Arvold, Nils D., Claus, Elizabeth B., Al-Mefty, Ossama, Johnson, Mark D., Golby, Alexandra J., Dunn, Ian F., Chiocca, E. Antonio, Trippa, Lorenzo, Santagata, Sandro, Folkerth, Rebecca D., Kantoff, Philip, Rollins, Barrett J., Lindeman, Neal I., Wen, Patrick Y., Ligon, Azra H., Beroukhim, Rameen, Alexander, Brian M., Ligon, Keith L.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
Basic and Translational Investigations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4578577/
https://ncbi.nlm.nih.gov/pubmed/25754088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nov015
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