Clinical multiplexed exome sequencing distinguishes adult oligodendroglial neoplasms from astrocytic and mixed lineage gliomas

Classifying adult gliomas remains largely a histologic diagnosis based on morphology; however astrocytic, oligodendroglial and mixed lineage tumors can display overlapping histologic features. We used multiplexed exome sequencing (OncoPanel) on 108 primary or recurrent adult gliomas, comprising 65 o...

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Publicado en:Oncotarget
Main Authors: Cryan, Jane B., Haidar, Sam, Ramkissoon, Lori A., Bi, Wenya Linda, Knoff, David S., Schultz, Nikolaus, Abedalthagafi, Malak, Brown, Loreal, Wen, Patrick Y., Reardon, David A., Dunn, Ian F., Folkerth, Rebecca D., Santagata, Sandro, Lindeman, Neal I., Ligon, Azra H., Beroukhim, Rameen, Hornick, Jason L., Alexander, Brian M., Ligon, Keith L., Ramkissoon, Shakti H.
Formato: Artigo
Idioma:Inglês
Publicado: Impact Journals LLC 2014
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Priority Research Paper
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4226668/
https://ncbi.nlm.nih.gov/pubmed/25257301
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