MAPK activation and HRAS mutation identified in pituitary spindle cell oncocytoma

Pituitary spindle cell oncocytoma (SCO) is an uncommon primary pituitary neoplasm that presents with mass effect on adjacent neurovascular structures, similar to non-hormone-producing pituitary adenomas. To determine the molecular etiology of SCO, we performed exome sequencing on four SCO cases, wit...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Miller, Michael B., Bi, Wenya Linda, Ramkissoon, Lori A., Kang, Yun Jee, Abedalthagafi, Malak, Knoff, David S., Agarwalla, Pankaj K., Wen, Patrick Y., Reardon, David A., Alexander, Brian M., Laws, Edward R., Dunn, Ian F., Beroukhim, Rameen, Ligon, Keith L., Ramkissoon, Shakti H.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5095058/
https://ncbi.nlm.nih.gov/pubmed/27175596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.9244
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