MAPK activation and HRAS mutation identified in pituitary spindle cell oncocytoma

Pituitary spindle cell oncocytoma (SCO) is an uncommon primary pituitary neoplasm that presents with mass effect on adjacent neurovascular structures, similar to non-hormone-producing pituitary adenomas. To determine the molecular etiology of SCO, we performed exome sequencing on four SCO cases, wit...

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Vydáno v:Oncotarget
Hlavní autoři: Miller, Michael B., Bi, Wenya Linda, Ramkissoon, Lori A., Kang, Yun Jee, Abedalthagafi, Malak, Knoff, David S., Agarwalla, Pankaj K., Wen, Patrick Y., Reardon, David A., Alexander, Brian M., Laws, Edward R., Dunn, Ian F., Beroukhim, Rameen, Ligon, Keith L., Ramkissoon, Shakti H.
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2016
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5095058/
https://ncbi.nlm.nih.gov/pubmed/27175596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.9244
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