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Leveraging molecular datasets for biomarker-based clinical trial design in glioblastoma

BACKGROUND. Biomarkers can improve clinical trial efficiency, but designing and interpreting biomarker-driven trials require knowledge of relationships among biomarkers, clinical covariates, and endpoints. We investigated these relationships across genomic subgroups of glioblastoma (GBM) within our...

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發表在:Neuro Oncol
Main Authors: Tanguturi, Shyam K., Trippa, Lorenzo, Ramkissoon, Shakti H., Pelton, Kristine, Knoff, David, Sandak, David, Lindeman, Neal I., Ligon, Azra H., Beroukhim, Rameen, Parmigiani, Giovanni, Wen, Patrick Y., Ligon, Keith L., Alexander, Brian M.
格式: Artigo
語言:Inglês
出版: Oxford University Press 2017
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5570228/
https://ncbi.nlm.nih.gov/pubmed/28339723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/now312
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