Leveraging molecular datasets for biomarker-based clinical trial design in glioblastoma

BACKGROUND. Biomarkers can improve clinical trial efficiency, but designing and interpreting biomarker-driven trials require knowledge of relationships among biomarkers, clinical covariates, and endpoints. We investigated these relationships across genomic subgroups of glioblastoma (GBM) within our...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Tanguturi, Shyam K., Trippa, Lorenzo, Ramkissoon, Shakti H., Pelton, Kristine, Knoff, David, Sandak, David, Lindeman, Neal I., Ligon, Azra H., Beroukhim, Rameen, Parmigiani, Giovanni, Wen, Patrick Y., Ligon, Keith L., Alexander, Brian M.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
Assuntos:
Basic and Translational Investigations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5570228/
https://ncbi.nlm.nih.gov/pubmed/28339723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/now312
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