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The contribution of homology arms to nuclease-assisted genome engineering
Designer nucleases like CRISPR/Cas9 enable fluent site-directed damage or small mutations in many genomes. Strategies for their use to achieve more complex tasks like regional exchanges for gene humanization or the establishment of conditional alleles are still emerging. To optimize Cas9-assisted ta...
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| Vydáno v: | Nucleic Acids Res |
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| Hlavní autoři: | , , , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Oxford University Press
2017
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5570031/ https://ncbi.nlm.nih.gov/pubmed/28582546 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx497 |
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