Engineered Zinc Finger Nuclease–Mediated Homologous Recombination of the Human Rhodopsin Gene

PURPOSE. Novel zinc finger nucleases (ZFNs) were designed to target the human rhodopsin gene and induce homologous recombination of a donor DNA fragment. METHODS. Three-finger zinc finger nucleases were designed based on previously published guidelines. To assay for ZFN specificity, the authors gene...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Greenwald, David L., Cashman, Siobhan M., Kumar-Singh, Rajendra
Format: Artigo
Sprog:Inglês
Udgivet: Association for Research in Vision and Ophthalmology, Inc. 2010
Fag:
Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3055761/
https://ncbi.nlm.nih.gov/pubmed/20671268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.10-5781
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker