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Differential requirement of SUFU in tissue development discovered in a hypomorphic mouse model
Suppressor of Fused (SUFU) is an essential negative regulator of the Hedgehog (HH) pathway and involved in GLI transcription factor regulation. Due to early embryonic lethality of Sufu(−/−) mice, investigations of SUFU’s role later in development are limited to conditional, tissue-specific knockout...
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| Udgivet i: | Dev Biol |
|---|---|
| Main Authors: | , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5569906/ https://ncbi.nlm.nih.gov/pubmed/28688895 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2017.06.037 |
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