Differential requirement of SUFU in tissue development discovered in a hypomorphic mouse model

Suppressor of Fused (SUFU) is an essential negative regulator of the Hedgehog (HH) pathway and involved in GLI transcription factor regulation. Due to early embryonic lethality of Sufu(−/−) mice, investigations of SUFU’s role later in development are limited to conditional, tissue-specific knockout...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Dev Biol
Asıl Yazarlar: Hoelzl, Maria A., Heby-Henricson, Karin, Gerling, Marco, Dias, José M., Kuiper, Raoul V., Trünkle, Cornelius, Bergström, Åsa, Ericson, Johan, Toftgård, Rune, Teglund, Stephan
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2017
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5569906/
https://ncbi.nlm.nih.gov/pubmed/28688895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2017.06.037
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