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Suppressor of Fused inhibits mammalian Hedgehog signaling in the absence of cilia

The Hedgehog (Hh) family of secreted proteins regulates mammalian development and cancer formation through Gli transcription factors, which exist in both activator and repressor forms. In vertebrates, the primary cilia play an essential role in Hh signal transduction and are required for both the ac...

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Bibliografske podrobnosti
Main Authors: Jia, Jinping, Kolterud, Åsa, Zeng, Huiqing, Hoover, Amber, Teglund, Stephan, Toftgård, Rune, Liu, Aimin
Format: Artigo
Jezik:Inglês
Izdano: 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2687323/
https://ncbi.nlm.nih.gov/pubmed/19371734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2009.04.009
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