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Suppressor of Fused inhibits mammalian Hedgehog signaling in the absence of cilia
The Hedgehog (Hh) family of secreted proteins regulates mammalian development and cancer formation through Gli transcription factors, which exist in both activator and repressor forms. In vertebrates, the primary cilia play an essential role in Hh signal transduction and are required for both the ac...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2687323/ https://ncbi.nlm.nih.gov/pubmed/19371734 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2009.04.009 |
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