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Distinct Activities of Gli1 and Gli2 in the Absence of Ift88 and the Primary Cilia
The primary cilia play essential roles in Hh-dependent Gli2 activation and Gli3 proteolytic processing in mammals. However, the roles of the cilia in Gli1 activation remain unresolved due to the loss of Gli1 transcription in cilia mutant embryos, and the inability to address this question by overexp...
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| 出版年: | J Dev Biol |
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| 主要な著者: | , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
MDPI
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6473256/ https://ncbi.nlm.nih.gov/pubmed/30791390 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jdb7010005 |
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