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Nitric Oxide Synthase and Structure-Based Inhibitor Design

Once it was discovered that the enzyme nitric oxide synthase (NOS) is responsible for the biosynthesis of NO, NOS became a drug target. Particularly important is the over production of NO by neuronal NOS (nNOS) in various neurodegenerative disorders. After the various NOS isoforms were identified, i...

詳細記述

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書誌詳細
出版年:Nitric Oxide
主要な著者: Poulos, Thomas L., Li, Huiying
フォーマット: Artigo
言語:Inglês
出版事項: 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5569579/
https://ncbi.nlm.nih.gov/pubmed/27890696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.niox.2016.11.004
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