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Nitric Oxide Synthase and Structure-Based Inhibitor Design
Once it was discovered that the enzyme nitric oxide synthase (NOS) is responsible for the biosynthesis of NO, NOS became a drug target. Particularly important is the over production of NO by neuronal NOS (nNOS) in various neurodegenerative disorders. After the various NOS isoforms were identified, i...
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| Publicado en: | Nitric Oxide |
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| Autores principales: | , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2016
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5569579/ https://ncbi.nlm.nih.gov/pubmed/27890696 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.niox.2016.11.004 |
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