Carregant...

Crystal Structures of Constitutive Nitric Oxide Synthases in Complex with De Novo Designed Inhibitors

New nitric oxide synthase (NOS) inhibitors were designed de novo with knowledge gathered from the studies on the nNOS-selective dipeptide inhibitors. Each of the new inhibitors consists of three fragments: an aminopyridine ring, a pyrrolidine, and a tail of various length and polarity. The in vitro...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Igarashi, Jotaro, Li, Huiying, Jamal, Joumana, Ji, Haitao, Fang, Jianguo, Lawton, Graham R., Silverman, Richard B., Poulos, Thomas L.
Format: Artigo
Idioma:Inglês
Publicat: 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3103786/
https://ncbi.nlm.nih.gov/pubmed/19296678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm900007a
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!