Selective Neuronal Nitric Oxide Synthase Inhibitors and the Prevention of Cerebral Palsy

OBJECTIVE: To design a new class of selective neuronal nitric oxide synthase (nNOS) inhibitors and demonstrate that administration in a rabbit model for cerebral palsy (CP) prevents hypoxia-ischemia induced deaths and reduces the number of newborn kits exhibiting signs of CP. METHODS: We used a nove...

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Detalhes bibliográficos
Main Authors: Ji, Haitao, Tan, Sidhartha, Igarashi, Jotaro, Li, Huiying, Derrick, Matthew, Martásek, Pavel, Roman, Linda J., Vásquez-Vivar, Jeannette, Poulos, Thomas L., Silverman, Richard B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2658647/
https://ncbi.nlm.nih.gov/pubmed/19235180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.21555
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