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Unexpected Binding Modes of Nitric Oxide Synthase Inhibitors Effective in the Prevention of Cerebral Palsy Phenotype in an Animal Model

Selective inhibition of the neuronal isoform of nitric oxide synthase NOS (nNOS) has been shown to prevent brain injury and is important for the treatment of various neurodegenerative disorders. However, given the high active site conservation among all three NOS isoforms, the design of selective in...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Delker, Silvia L, Ji, Haitao, Li, Huiying, Jamal, Joumana, Fang, Jianguo, Xue, Fengtian, Silverman, Richard B., Poulos, Thomas L.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2010
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3202968/
https://ncbi.nlm.nih.gov/pubmed/20337441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja910228a
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