Učitavanje...

Crystal Structures of Constitutive Nitric Oxide Synthases in Complex with De Novo Designed Inhibitors

New nitric oxide synthase (NOS) inhibitors were designed de novo with knowledge gathered from the studies on the nNOS-selective dipeptide inhibitors. Each of the new inhibitors consists of three fragments: an aminopyridine ring, a pyrrolidine, and a tail of various length and polarity. The in vitro...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Glavni autori: Igarashi, Jotaro, Li, Huiying, Jamal, Joumana, Ji, Haitao, Fang, Jianguo, Lawton, Graham R., Silverman, Richard B., Poulos, Thomas L.
Format: Artigo
Jezik:Inglês
Izdano: 2009
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3103786/
https://ncbi.nlm.nih.gov/pubmed/19296678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm900007a
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!