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A population-epigenetic model to infer site-specific methylation rates from double-stranded DNA methylation patterns
Cytosine methylation is an epigenetic mechanism in eukaryotes that is often associated with stable transcriptional silencing, such as in X-chromosome inactivation and genomic imprinting. Aberrant methylation patterns occur in several inherited human diseases and in many cancers. To understand how me...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2005
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC556300/ https://ncbi.nlm.nih.gov/pubmed/15827124 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0502036102 |
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