Hairpin-bisulfite PCR: Assessing epigenetic methylation patterns on complementary strands of individual DNA molecules

Epigenetic inheritance, the transmission of gene expression states from parent to daughter cells, often involves methylation of DNA. In eukaryotes, cytosine methylation is a frequent component of epigenetic mechanisms. Failure to transmit faithfully a methylated or an unmethylated state of cytosine...

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Autors principals: Laird, Charles D., Pleasant, Nicole D., Clark, Aaron D., Sneeden, Jessica L., Hassan, K. M. Anwarul, Manley, Nathan C., Vary, Jay C., Morgan, Todd, Hansen, R. Scott, Stöger, Reinhard
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2004
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC314163/
https://ncbi.nlm.nih.gov/pubmed/14673087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2536758100
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