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The Size of the Internal Loop in DNA Hairpins Influences Their Targeting with Partially Complementary Strands
[Image: see text] Targeting of noncanonical DNA structures, such as hairpin loops, may have significant diagnostic and therapeutic potential. Oligonucleotides can be used for binding to mRNA, forming a DNA/RNA hybrid duplex that inhibits translation. This kind of modulation of gene expression is cal...
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| Publicado no: | J Phys Chem B |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Chemical
Society
2014
|
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4291056/ https://ncbi.nlm.nih.gov/pubmed/25486129 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp510131c |
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