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Errors in the bisulfite conversion of DNA: modulating inappropriate- and failed-conversion frequencies
Bisulfite treatment can be used to ascertain the methylation states of individual cytosines in DNA. Ideally, bisulfite treatment deaminates unmethylated cytosines to uracils, and leaves 5-methylcytosines unchanged. Two types of bisulfite-conversion error occur: inappropriate conversion of 5-methylcy...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2602783/ https://ncbi.nlm.nih.gov/pubmed/18984622 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkn691 |
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