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Asymmetric Strand Segregation: Epigenetic Costs of Genetic Fidelity?
Asymmetric strand segregation has been proposed as a mechanism to minimize effective mutation rates in epithelial tissues. Under asymmetric strand segregation, the double-stranded molecule that contains the oldest DNA strand is preferentially targeted to the somatic stem cell after each round of DNA...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2684645/ https://ncbi.nlm.nih.gov/pubmed/19503601 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1000509 |
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