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Genetic and epigenetic control of the efficiency and fidelity of cross-species prion transmission

Self-perpetuating amyloid-based protein isoforms (prions) transmit neurodegenerative diseases in mammals and phenotypic traits in yeast. Although mechanisms that control species-specificity of prion transmission are poorly understood, studies of closely related orthologs of yeast prion protein Sup35...

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Bibliografiske detaljer
Main Authors: Chen, Buxin, Bruce, Kathryn L., Newnam, Gary P., Gyoneva, Stefka, Romanyuk, Andrey V., Chernoff, Yury O.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3025758/
https://ncbi.nlm.nih.gov/pubmed/20444092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2958.2010.07177.x
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