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Contributions of the Prion Protein Sequence, Strain, and Environment to the Species Barrier
Amyloid propagation requires high levels of sequence specificity so that only molecules with very high sequence identity can form cross-β-sheet structures of sufficient stringency for incorporation into the amyloid fibril. This sequence specificity presents a barrier to the transmission of prions be...
Gardado en:
| Publicado en: | J Biol Chem |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2016
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4714215/ https://ncbi.nlm.nih.gov/pubmed/26565023 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.684100 |
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