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Contributions of the Prion Protein Sequence, Strain, and Environment to the Species Barrier

Amyloid propagation requires high levels of sequence specificity so that only molecules with very high sequence identity can form cross-β-sheet structures of sufficient stringency for incorporation into the amyloid fibril. This sequence specificity presents a barrier to the transmission of prions be...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:J Biol Chem
Asıl Yazarlar: Sharma, Aditi, Bruce, Kathryn L., Chen, Buxin, Gyoneva, Stefka, Behrens, Sven H., Bommarius, Andreas S., Chernoff, Yury O.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Biochemistry and Molecular Biology 2016
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4714215/
https://ncbi.nlm.nih.gov/pubmed/26565023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.684100
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