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A population-epigenetic model to infer site-specific methylation rates from double-stranded DNA methylation patterns

Cytosine methylation is an epigenetic mechanism in eukaryotes that is often associated with stable transcriptional silencing, such as in X-chromosome inactivation and genomic imprinting. Aberrant methylation patterns occur in several inherited human diseases and in many cancers. To understand how me...

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Bibliografski detalji
Glavni autori: Genereux, Diane P., Miner, Brooks E., Bergstrom, Carl T., Laird, Charles D.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2005
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC556300/
https://ncbi.nlm.nih.gov/pubmed/15827124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0502036102
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