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STATISTICAL INFERENCE OF TRANSMISSION FIDELITY OF DNA METHYLATION PATTERNS OVER SOMATIC CELL DIVISIONS IN MAMMALS

We develop Bayesian inference methods for a recently-emerging type of epigenetic data to study the transmission fidelity of DNA methylation patterns over cell divisions. The data consist of parent-daughter double-stranded DNA methylation patterns with each pattern coming from a single cell and repre...

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Detalhes bibliográficos
Main Authors: Fu, Audrey Qiuyan, Genereux, Diane P., Stöger, Reinhard, Laird, Charles D., Stephens, Matthew
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3103139/
https://ncbi.nlm.nih.gov/pubmed/21625348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1214/09-AOAS297SUPPA
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