Prospective Genomic Profiling of Prostate Cancer Across Disease States Reveals Germline and Somatic Alterations That May Affect Clinical Decision Making

PURPOSE: A long natural history and a predominant osseous pattern of metastatic spread are impediments to the adoption of precision medicine in patients with prostate cancer. To establish the feasibility of clinical genomic profiling in this disease, we performed targeted deep sequencing of tumor an...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:JCO Precis Oncol
Hauptverfasser: Abida, Wassim, Armenia, Joshua, Gopalan, Anuradha, Brennan, Ryan, Walsh, Michael, Barron, David, Danila, Daniel, Rathkopf, Dana, Morris, Michael, Slovin, Susan, McLaughlin, Brigit, Curtis, Kristen, Hyman, David M., Durack, Jeremy C., Solomon, Stephen B., Arcila, Maria E., Zehir, Ahmet, Syed, Aijazuddin, Gao, Jianjiong, Chakravarty, Debyani, Vargas, Hebert Alberto, Robson, Mark E., Vijai, Joseph, Offit, Kenneth, Donoghue, Mark T.A., Abeshouse, Adam A., Kundra, Ritika, Heins, Zachary J., Penson, Alexander V., Harris, Christopher, Taylor, Barry S., Ladanyi, Marc, Mandelker, Diana, Zhang, Liying, Reuter, Victor E., Kantoff, Philip W., Solit, David B., Berger, Michael F., Sawyers, Charles L., Schultz, Nikolaus, Scher, Howard I.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Clinical Oncology 2017
Schlagworte:
Original Reports
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5558263/
https://ncbi.nlm.nih.gov/pubmed/28825054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/PO.17.00029
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge