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Kinetic Isotope Effects and Transition State Structure for Human Phenylethanolamine N-Methyltransferase

Phenylethanolamine N-methyltransferase (PNMT) catalyzes the S-adenosyl-l-methionine (SAM)-dependent conversion of norepinephrine to epinephrine. Epinephrine has been associated with critical processes in humans including the control of respiration and blood pressure. Additionally, PNMT activity has...

詳細記述

保存先:
書誌詳細
出版年:ACS Chem Biol
主要な著者: Stratton, Christopher F., Poulin, Myles B., Du, Quan, Schramm, Vern L.
フォーマット: Artigo
言語:Inglês
出版事項: 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5553282/
https://ncbi.nlm.nih.gov/pubmed/27997103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.6b00922
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