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Kinetic Isotope Effects and Transition State Structure for Human Phenylethanolamine N-Methyltransferase
Phenylethanolamine N-methyltransferase (PNMT) catalyzes the S-adenosyl-l-methionine (SAM)-dependent conversion of norepinephrine to epinephrine. Epinephrine has been associated with critical processes in humans including the control of respiration and blood pressure. Additionally, PNMT activity has...
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| Izdano u: | ACS Chem Biol |
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| Glavni autori: | , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2016
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5553282/ https://ncbi.nlm.nih.gov/pubmed/27997103 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.6b00922 |
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