Platelet microparticles infiltrating solid tumors transfer miRNAs that suppress tumor growth

Platelet-derived microparticles (PMPs) are associated with enhancement of metastasis and poor cancer outcomes. Circulating PMPs transfer platelet microRNAs (miRNAs) to vascular cells. Solid tumor vasculature is highly permeable, allowing the possibility of PMP–tumor cell interaction. Here, we show t...

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Detalles Bibliográficos
Publicado en:Blood
Main Authors: Michael, James V., Wurtzel, Jeremy G. T., Mao, Guang Fen, Rao, A. Koneti, Kolpakov, Mikhail A., Sabri, Abdelkarim, Hoffman, Nicholas E., Rajan, Sudarsan, Tomar, Dhanendra, Madesh, Muniswamy, Nieman, Marvin T., Yu, Johnny, Edelstein, Leonard C., Rowley, Jesse W., Weyrich, Andrew S., Goldfinger, Lawrence E.
Formato: Artigo
Idioma:Inglês
Publicado: American Society of Hematology 2017
Assuntos:
Plenary Paper
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5542851/
https://ncbi.nlm.nih.gov/pubmed/28500171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2016-11-751099
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