Platelet microparticles infiltrating solid tumors transfer miRNAs that suppress tumor growth

Platelet-derived microparticles (PMPs) are associated with enhancement of metastasis and poor cancer outcomes. Circulating PMPs transfer platelet microRNAs (miRNAs) to vascular cells. Solid tumor vasculature is highly permeable, allowing the possibility of PMP–tumor cell interaction. Here, we show t...

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Bibliografske podrobnosti
izdano v:Blood
Main Authors: Michael, James V., Wurtzel, Jeremy G. T., Mao, Guang Fen, Rao, A. Koneti, Kolpakov, Mikhail A., Sabri, Abdelkarim, Hoffman, Nicholas E., Rajan, Sudarsan, Tomar, Dhanendra, Madesh, Muniswamy, Nieman, Marvin T., Yu, Johnny, Edelstein, Leonard C., Rowley, Jesse W., Weyrich, Andrew S., Goldfinger, Lawrence E.
Format: Artigo
Jezik:Inglês
Izdano: American Society of Hematology 2017
Teme:
Plenary Paper
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5542851/
https://ncbi.nlm.nih.gov/pubmed/28500171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2016-11-751099
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