Platelet microparticles infiltrating solid tumors transfer miRNAs that suppress tumor growth

Platelet-derived microparticles (PMPs) are associated with enhancement of metastasis and poor cancer outcomes. Circulating PMPs transfer platelet microRNAs (miRNAs) to vascular cells. Solid tumor vasculature is highly permeable, allowing the possibility of PMP–tumor cell interaction. Here, we show t...

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Dades bibliogràfiques
Publicat a:Blood
Autors principals: Michael, James V., Wurtzel, Jeremy G. T., Mao, Guang Fen, Rao, A. Koneti, Kolpakov, Mikhail A., Sabri, Abdelkarim, Hoffman, Nicholas E., Rajan, Sudarsan, Tomar, Dhanendra, Madesh, Muniswamy, Nieman, Marvin T., Yu, Johnny, Edelstein, Leonard C., Rowley, Jesse W., Weyrich, Andrew S., Goldfinger, Lawrence E.
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2017
Matèries:
Plenary Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5542851/
https://ncbi.nlm.nih.gov/pubmed/28500171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2016-11-751099
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