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Dicer1-mediated miRNA processing shapes the mRNA profile and function of murine platelets
Human platelets contain microRNAs (miRNAs) and miRNA processing machinery, but their contribution to platelet function remains incompletely understood. Here, we show that murine megakaryocyte (MK)-specific knockdown of Dicer1, the ribonuclease that cleaves miRNA precursors into mature miRNAs, reduce...
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| Publicado no: | Blood |
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| Main Authors: | , , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Hematology
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4825412/ https://ncbi.nlm.nih.gov/pubmed/26773046 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2015-07-661371 |
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