Dicer1-mediated miRNA processing shapes the mRNA profile and function of murine platelets

Human platelets contain microRNAs (miRNAs) and miRNA processing machinery, but their contribution to platelet function remains incompletely understood. Here, we show that murine megakaryocyte (MK)-specific knockdown of Dicer1, the ribonuclease that cleaves miRNA precursors into mature miRNAs, reduce...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Blood
मुख्य लेखकों: Rowley, Jesse W., Chappaz, Stéphane, Corduan, Aurélie, Chong, Mark M. W., Campbell, Robert, Khoury, Amanda, Manne, Bhanu Kanth, Wurtzel, Jeremy G. T., Michael, James V., Goldfinger, Lawrence E., Mumaw, Michele M., Nieman, Marvin T., Kile, Benjamin T., Provost, Patrick, Weyrich, Andrew S.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society of Hematology 2016
विषय:
Plenary Paper
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4825412/
https://ncbi.nlm.nih.gov/pubmed/26773046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2015-07-661371
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