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Increase of MET gene copy number confers resistance to a monovalent MET antibody and establishes drug dependence
The relevant role in cancer played by the tyrosine kinase receptor encoded by the MET oncogene led to the development of specific inhibitors, some of which are now in advanced phases of clinical trials. Previous experience has shown that the main limit to the efficacy of most targeted treatments is...
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| Publicado en: | Mol Oncol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
John Wiley and Sons Inc.
2014
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5528600/ https://ncbi.nlm.nih.gov/pubmed/25011627 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2014.06.010 |
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