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Monovalency Unleashes the Full Therapeutic Potential of the DN-30 Anti-Met Antibody
Met, the high affinity receptor for hepatocyte growth factor, is one of the most frequently activated tyrosine kinases in human cancer and a validated target for cancer therapy. We previously developed a mouse monoclonal antibody directed against the extracellular portion of Met (DN-30) that induces...
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| 主要な著者: | , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Biochemistry and Molecular Biology
2010
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2975237/ https://ncbi.nlm.nih.gov/pubmed/20833723 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.134031 |
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