Загрузка...

Inhibition of ligand‐independent constitutive activation of the Met oncogenic receptor by the engineered chemically‐modified antibody DN30

An awesome number of experimental and clinical evidences indicate that constitutive activation of the Met oncogenic receptor plays a critical role in the progression of cancer toward metastasis and/or resistance to targeted therapies. While mutations are rare, the common mechanism of Met activation...

Полное описание

Сохранить в:
Библиографические подробности
Опубликовано в: :Mol Oncol
Главные авторы: Vigna, Elisa, Chiriaco, Cristina, Cignetto, Simona, Fontani, Lara, Basilico, Cristina, Petronzelli, Fiorella, Comoglio, Paolo M.
Формат: Artigo
Язык:Inglês
Опубликовано: John Wiley and Sons Inc. 2015
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5528712/
https://ncbi.nlm.nih.gov/pubmed/26119717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2015.05.007
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!