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An ‘in‐cell trial’ to assess the efficacy of a monovalent anti‐MET antibody as monotherapy and in association with standard cytotoxics

In clinical practice, targeted therapies are usually administered together with chemotherapeutics. However, little is known whether conventional cytotoxic agents enhance the efficacy of targeted compounds, and whether a possible synergy would be dictated by drug‐sensitizing genetic alterations. To e...

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Vydáno v:Mol Oncol
Hlavní autoři: Benvenuti, Silvia, Gentile, Alessandra, Lazzari, Luca, Arnesano, Addolorata, Trusolino, Livio, Comoglio, Paolo M.
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5528555/
https://ncbi.nlm.nih.gov/pubmed/24389243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2013.12.006
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