PVT1 dependence in cancer with MYC copy-number increase

‘Gain’ of supernumerary copies of the 8q24.21 chromosomal region has been shown to be common in many human cancers(1–13) and is associated with poor prognosis(7,10,14). The well-characterized myelocytomatosis (MYC) oncogene resides in the 8q24.21 region and is consistently co-gained with an adjacent...

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Bibliografske podrobnosti
izdano v:Nature
Main Authors: Tseng, Yuen-Yi, Moriarity, Branden S., Gong, Wuming, Akiyama, Ryutaro, Tiwari, Ashutosh, Kawakami, Hiroko, Ronning, Peter, Reuland, Brian, Guenther, Kacey, Beadnell, Thomas C., Essig, Jaclyn, Otto, George M., O’Sullivan, M. Gerard, Largaespada, David A., Schwertfeger, Kathryn L., Marahrens, York, Kawakami, Yasuhiko, Bagchi, Anindya
Format: Artigo
Jezik:Inglês
Izdano: 2014
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4767149/
https://ncbi.nlm.nih.gov/pubmed/25043044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature13311
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