PVT1 dependence in cancer with MYC copy-number increase

‘Gain’ of supernumerary copies of the 8q24.21 chromosomal region has been shown to be common in many human cancers(1–13) and is associated with poor prognosis(7,10,14). The well-characterized myelocytomatosis (MYC) oncogene resides in the 8q24.21 region and is consistently co-gained with an adjacent...

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Publicado en:Nature
Main Authors: Tseng, Yuen-Yi, Moriarity, Branden S., Gong, Wuming, Akiyama, Ryutaro, Tiwari, Ashutosh, Kawakami, Hiroko, Ronning, Peter, Reuland, Brian, Guenther, Kacey, Beadnell, Thomas C., Essig, Jaclyn, Otto, George M., O’Sullivan, M. Gerard, Largaespada, David A., Schwertfeger, Kathryn L., Marahrens, York, Kawakami, Yasuhiko, Bagchi, Anindya
Formato: Artigo
Idioma:Inglês
Publicado: 2014
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4767149/
https://ncbi.nlm.nih.gov/pubmed/25043044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature13311
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