Sall4-Gli3 system in early limb progenitors is essential for the development of limb skeletal elements

Limb skeletal elements originate from the limb progenitor cells, which undergo expansion and patterning to develop each skeletal element. Posterior-distal skeletal elements, such as the ulna/fibula and posterior digits develop in a Sonic hedgehog (Shh)-dependent manner. However, it is poorly underst...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Akiyama, Ryutaro, Kawakami, Hiroko, Wong, Julia, Oishi, Isao, Nishinakamura, Ryuichi, Kawakami, Yasuhiko
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2015
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4413345/
https://ncbi.nlm.nih.gov/pubmed/25848055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1421949112
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