Activation of HER family members in gastric carcinoma cells mediates resistance to MET inhibition

BACKGROUND: Gastric cancer is the second leading cause of cancer mortality in the world. The receptor tyrosine kinase MET is constitutively activated in many gastric cancers and its expression is strictly required for survival of some gastric cancer cells. Thus, MET is considered a good candidate fo...

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Bibliografiske detaljer
Main Authors: Corso, Simona, Ghiso, Elena, Cepero, Virna, Sierra, J Rafael, Migliore, Cristina, Bertotti, Andrea, Trusolino, Livio, Comoglio, Paolo M, Giordano, Silvia
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2010
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2892452/
https://ncbi.nlm.nih.gov/pubmed/20500904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-9-121
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