Activation of HER family members in gastric carcinoma cells mediates resistance to MET inhibition

BACKGROUND: Gastric cancer is the second leading cause of cancer mortality in the world. The receptor tyrosine kinase MET is constitutively activated in many gastric cancers and its expression is strictly required for survival of some gastric cancer cells. Thus, MET is considered a good candidate fo...

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Autores principales: Corso, Simona, Ghiso, Elena, Cepero, Virna, Sierra, J Rafael, Migliore, Cristina, Bertotti, Andrea, Trusolino, Livio, Comoglio, Paolo M, Giordano, Silvia
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2010
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2892452/
https://ncbi.nlm.nih.gov/pubmed/20500904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-9-121
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